Logical gates in actin monomer

© 2017 The Author(s). We evaluate information processing capacity of a single actin molecule by calculating distributions of logical gates implemented by the molecule via propagating patterns of excitation. We represent a filamentous actin molecule as an excitable automaton network (F-actin automaton). where every atom updates its state depending on states of atoms its connected to with chemical bonds (hard neighbours) and atoms being in physical proximity to the atom (soft neighbours). A resting atom excites if a sum of its excited hard neighbours and a weighted sum of its soft neighbours belong to some specified interval. We demonstrate that F-actin automata implement OR, AND, XOR and AND-NOT gates via interacting patterns of excitation. Gate AND is the most common gate and gate XOR is the rarest. Using the architectures of gates discovered we implement one bit half-adder and controlled-not circuits in the F-actin automata. Speed and space values of the F-actin molecular computers are discussed

QUANTUM INFORMATION METHODS FOR ENTANGLEMENT COMPUTATION: THE CASE OF THE HELIUM ATOM.

The thesis aims to study the applicability of techniques of Quantum Information theory to complex systems, like molecules and biomolecules. Recently, concepts of Quantum Information theory have been applied to the study of phenomena involving molecules, for instance the interaction light-biomolecules. In particular, the entanglement has been proposed to quantify the non-classicality of interactions. The computation of molecular structures and interactions, on the other hand, has been studied for decades mainly to understand reactions\u2019 kinetic and energetic characteristics. It is not straightforward to apply these methods to the computation of quantum correlations. We have therefore explored the computability of such effects using Quantum Information techniques. We started with the study of the electronic correlations in the Helium atom, that is the simplest non trivial case, in order to evaluate the computational problems and to develop approximate methods suitable to more complex systems. We start recalling the definition and basic properties of entanglement, as it is considered in Quantum Information theory. We illustrate how it can be measured and the difficulties one encounters when identical particles are involved, then we concentrate on the case of Helium in particular. In order to study the entanglement in Helium, we treat separately the singlet and the triplet configurations. The method we use consists in computing the reduced density matrix and then the entropy. The possible choices of coordinates, basis functions and computation strategies are discussed, together with their impact on the algorithms. The reduced, single-electron von Neumann and linear entropy for several low-energy eigenstates of Helium are computed by means of a simple configuration-interaction variational method

N=1* model superpotential revisited (IR behaviour of N=4 limit)

The one-loop contribution to the superpotential, in particular the Veneziano-Yankielowicz potential in N=1 supersymmetric Yang-Mills model is discussed from an elementary field theory method and the matrix model point of view. Both approaches are based on the Renormalization Group variation of the superconformal N=4 supersymmetric Yang-Mills model.Comment: 31 page

Comparison of ECMWF surface meteorology and buoy observations in the Ligurian Sea

Since numerical weather prediction (NWP) models are usually used to force ocean circulation models, it is important to investigate their skill in reproducing surface meteorological parameters in open sea conditions. Near-surface meteorological data (air temperature, relative humidity, barometric pressure, wind speed and direction) have been acquired from several sensors deployed on an offshore large spar buoy in the Ligurian Sea (Northern Mediterranean Sea) from February to December 2000. The buoy collected 7857 valid records out of 8040 during 335 days at sea. These observations have been compared with data from NWP models and specifically, the outputs of the ECMWF analysis in the two grid points closest to the buoy position. Hourly data acquired by the buoy have been undersampled to fit the data set of the model composed by values computed at the four synoptic hours. For each mentioned meteorological parameter an analysis has been performed by evaluating instantaneous synoptic differences, distributions, daily and annual variations and related statistics. The comparison shows that the model reproduces correctly the baric field while significant differences result for the other variables, which are more affected by local conditions. This suggests that the observed discrepancies may be due to the poor resolution of the model that probably is not sufficient to appropriately discriminate between land and ocean surfaces in a small basin such as the Ligurian Sea and to take into account local peculiarities. The use of time- and space-averaged model data reduces the differences with respect to the in situ observations, thus making the model data usable for analysis with minor requirements about time and space resolution. Although this comparison is strongly limited and we cannot exclude measurement errors, its results suggest a great caution in the use of the model data, especially at high frequency resolution. They may lead to incorrect estimates of atmospheric forcing into ocean circulation models, causing important errors in those areas, such as the Mediterranean Sea, where ocean circulation is strongly coupled with atmosphere and its high variability

Design of a Base-Board for arrays of closely-packed Multi-Anode Photo-Multipliers

We describe the design of a Base-Board to house Multi-Anode Photo-Multipliers for use in large-area arrays of light sensors. The goals, the design, the results of tests on the prototypes and future developments are presented.Comment: 16 pages, 5 figures, submitted to Nucl. Instrum. and Meth.

A hydrological analysis of the 4 November 2011 event in Genoa

On the 4 November 2011 a flash flood event hit the area of Genoa with dramatic consequences. Such an event represents, from the meteorological and hydrological perspective, a paradigm of flash floods in the Mediterranean environment. <br><br> The hydro-meteorological probabilistic forecasting system for small and medium size catchments in use at the Civil Protection Centre of Liguria region exhibited excellent performances for the event, by predicting, 24–48 h in advance, the potential level of risk associated with the forecast. It greatly helped the decision makers in issuing a timely and correct alert. <br><br> In this work we present the operational outputs of the system provided during the Liguria events and the post event hydrological modelling analysis that has been carried out accounting also for the crowd sourcing information and data. We discuss the benefit of the implemented probabilistic systems for decision-making under uncertainty, highlighting how, in this case, the multi-catchment approach used for predicting floods in small basins has been crucial

Analysis and hindcast simulations of an extreme rainfall event in the Mediterranean area: The Genoa 2011 case

n/